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Current Approaches for Reducing Treatment Toxicities in Radiotherapy Side Effects Management

Year: 2025
Type: article
Abstract: Radiotherapy is an important part of treating many types of cancer because it targets and kills cancerous cells. But even though it works well as a treatment, it often has bad side effects because it exposes good cells around the tumor to radiation without meaning to. These side effects can be very harmful during treatment, lowering the quality of life for the patient and maybe even making it harder to give the tumor the right amount of radiation. Recent improvements in radiation treatments and ways to deal with side effects have focused on reducing these harmful effects while keeping the treatment effective. One important way to lower the side effects of radiotherapy is to improve the way the treatment is given. Different methods, like intensity-modulated radiation therapy (IMRT), image-guided radiation therapy (IGRT), and proton therapy, make it possible to give radiation more precisely, protecting good cells around the tumor from too much exposure. These methods use high-tech imaging methods and complex computer programs to precisely target tumors and lower the risk of side effects. Using tailored radiation, which takes into account changes in the body and anatomy during treatment, makes treatment even more accurate. Along with improvements in technology, a multidisciplinary approach to managing toxins has become more important. Combining drug treatments, like radioprotectors and tailored therapies, has been looked into as a way to lessen the damage that radiation does to healthy cells. The goal of these chemicals is to protect healthy cells from radiation damage while not affecting the treatment of cancer cells. Biomarker-based methods are also making it easier to predict and customize treatment plans.
Language: English
Subfield: Radiation
Open Access status: diamond
OpenAlex ID: W4414047813
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Cites: 23
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Related to: 10