Aliarcobacter butzleri colitis in rhesus macaques ( Macaca mulatta )
Year: 2025
Type: article
Abstract: Aliarcobacter butzleri is a Campylobacter -like bacteria associated with watery diarrhea in humans and is infrequently reported in nonhuman primate (NHP) populations. While clinical and microscopic features in humans are indistinguishable from Campylobacter spp. infection, descriptions of A. butzleri -associated colitis in NHP are lacking. Here, we describe the clinical and pathological features of diarrhea and colitis associated with A. butzleri in rhesus macaques using a retrospective approach. Over a 3-year period, A. butzleri was isolated from 10 macaques with diarrhea. Five of the 10 were submitted for necropsy and had features of chronic enterocolitis, consistent with existing literature. However, 40% (2/5) of the cases were characterized by ulcerative colitis, which has not previously been described as a feature of A. butzleri colitis. A. butzleri should be considered a differential diagnosis in cases of diarrhea and enterocolitis in captive rhesus macaques.
Source: Veterinary Pathology
Authors: Adam K. Myers, Ahmad A. Saied, Tessa J. Williams, Robin L. Sherar, Kathrine P. Falkenstein, Peter J. Didier, Jason P. Dufour, Krystal J. Vail
Institution: Tulane University
Language: English
Subfield: Food Science
Domain: Life Sciences
Open Access status: green
Awards: G2462596300, G39035037, G7045095313, G8198088040, Tulane National Primate Research Center, Role of LRRK2 in immunity in a nonhuman primate model of SIV, Maintenance of an SPF Macaque Breeding Colony for AIDS Research, Tulane National Primate Research Center AIDS SPF Breeding Colony Maintenance
OpenAlex ID: W4414081963