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Systemic Delivery of an mRNA-Encoding, Tumor-Activated Interleukin-12 Lock to Eliminate Tumors and Avoid Immune-Related Adverse Events

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Year: 2025
Type: article
Source: Nano Letters
DOI: 10.1021/acs.nanolett.5c03454
Authors: Cai Yang, Lizhuan Zhang, Yuying Yang, Minhui Su, Mengyuan Jiang, Juncai Li, Dailiang Zhang, Yang Sun, Ding Ding, Haoran Jia, Sitao Xie, Xiangsheng Liu, Ting Fu, Cheng Cui, Zhen Du, Weihong Tan
Institutions: Hunan University, Chinese Academy of Sciences, Zhejiang Cancer Hospital, State Key Laboratory of Chemobiosensing and Chemometrics, Hangzhou Institute of Medicine, Chinese Academy of Sciences, Shanghai Jiao Tong University, Renji Hospital
Language: English

Topic: RNA Interference and Gene Delivery
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, National Key Research and Development Program of China
Awards: G1092239889, G1688021431, G5089357767, G5987082150, G6424538339, G8230092021, G9000207710
OpenAlex ID: W4414083944
FWCI: 0.761
Cites: 39
Cited by: 3
Related to: 10
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