Work

Grades 3 and 4 adult-type diffuse gliomas: epidemiology and radiomics in Guanajuato, Mexico

Year: 2025

Type: article

Abstract: Objective: The objective of the study is to report epidemiological characteristics and prognostic factors of patients with adult-type gliomas treated in the neurosurgery department of the National Medical Center of Bajío, as well as to evaluate, for the 1 st time in Mexican patients, surface regularity (SR).Methods: Epidemiological and clinical features were statistically compared with international references.Survival was estimated using the Kaplan-Meier method.Kaplan-Meier curves were compared with the log-rank test.SR was obtained by segmenting magnetic resonance imaging.Results: Median age of patients with glioblastomas was less than that of patients in the United States (p = 0.021).The administration of radiotherapy (RT) and temozolomide (TMZ) prolonged survival (median gain of 35 months).Median SR was 0.6006 and was close to being statistically lower than the value reported in a large cohort (p = 0.09).Conclusions: Glioblastomas were diagnosed at younger ages and appeared to be more aggressive.The administration of RT and TMZ prolonged substantially survival.

Source: Revista de Fomento Social

DOI: 10.24875/rmn.25000005

Authors: Luis E. Ayala-Hernández, Raúl Gómez-Gómez, Armando Gallegos, Raúl A. Hernández-Estrada

Institutions: Hospital de Especialidades, Universidad de Guadalajara

Language: English

Topic: Glioma Diagnosis and Treatment

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4414089436