Equitable access to a personalized treatment with the OncoCREAN national strategy in pediatric patients with acute lymphoblastic leukemia from the Mexican Social Security Institute
Year: 2025
Type: article
Abstract: Introduction: The Mexican Social Security Institute (IMSS) was created in 1943 as the main public institution in Mexico. Methods: In 2020, the OncoCREAN (Centros de Referencia Estatal para la Atención del Niño y de la Niña con Cáncer) strategy was established and consists of reference centers of Pediatric Oncology created to provide equitable access to pediatric patients with cancer in Mexico and toimprove the disease survival through standardized immunophenotyping, harmonized diagnosis, homogenized treatment, staff training, and complication response. Results: At 12 months of follow-up, overall survival is 89.9% in pediatric patients with acute lymphoblastic leukemia; we have no early death, and the main cause of death is still infection. Discussion: The current procedure in terms of immune molecular diagnosis is to send samples to the first national system of samples reference for the immunological diagnosis of leukemias based on immunophenotyping in the Cytomics Laboratory of the IMSS Research Center in Puebla, as a strong collaborative alliance. We present a narrative description of the strategy as preliminary results.
Source: Frontiers in Oncology
Authors: Enrique Lopez Aguilar, Angeles Del Campo Martinez, Ana Rioscovian Soto, Karen Ayala-Contreras, Marta Zapata-Tarrés, Miguel Enrique Cuéllar Mendoza, Yadira Betanzos Cabrera, Regina Zevada-Mosti, Sheyla Payán Romo, Oscar Omar Esquer Cota, Pamela Zazueta Mérida, Susana Elizabeth Anaya Aguirre, Emmanuel Rolando Rodríguez Cedeño, Maria De Lourdes Gutiérrez Rivera, Jorge Alfonso Martín Trejo, Elvia Yaroslab Mayorga Castillo, Carolina Contreras Camacho, Elio Aaron Reyes Espinoza, Norma Eryca Alatoma Medina, Hector Manuel Tiznado García, Christian Santillán Ávila, Jose Maria Sepúlveda Núñez, Sadya Fuerte Olvera, Lizeth Rodríguez Brindis, Jose Alvaro Parra Salazar, Lilia Adela García Stivalet, Lizette Bojórquez Steffani, Roberto Abraham Betancourt Ortiz, Aurora Treviño, Julio Mercado Castruita, Rocio Aburto Mejia, Adrian Jimenez Salinas, Francisco Javier Valdivia Ibarra, Fabiana Maribel Zepeda Arias, Ana Leticia Figueroa Rosas, Desiree Sagarnaga Durante, Fatima Borrego Perez, Jorge Humberto Urbina Ochoa, Gustavo Ignacio Prieto Torres, Jose De Jesus Chavez Martenez, Juan Gilberto Perez Soltero, Guillermo Careaga Reyna, Ma. Teresa Cristina Ramos Hernandez, Rocio Cardenas Navarrete, Elsa Fabiola Gonzalez Rosas, Adolfo Pineda Gordillo, Cecilia Ochoa-Drucker, Enrique López Facio, Mirna Guadalupe Rios Osuna, Claudia Selene Portillo Zavala, Sergio Ruben Cobo Ovando, A. B. Aguilar Román, Brenda Chávez Liñán, Benjamin Arroyo Acosta, Luis E. Bernabe-Gaspar, A. B. Rivera Ramírez, D. A. Malváez Estrada, E. Ulloa Salaices, V. P. Silva Delfín, G. González Villarreal, M. Estolando Ayón, Aaron Muñoz Flores, E. F. Ortiz de la O, H. J. Ortiz Trujillo, José Luis Moreno Domínguez, Miguel Lopez Suastegui, L. Gallegos Cruz, Celida Duque-Molina
Institution: Mexican Social Security Institute
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,801
OpenAlex ID: W4414096061