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A case of Kawasaki disease refractory to initial intravenous immunoglobulin therapy linked to febrile seizures at Japanese Red Cross Maebashi Hospital, Japan

Year: 2025

Type: article

Abstract: Febrile seizures (FS) and Kawasaki disease (KD) are both common pediatric conditions among the Asian population. However, FS rarely occur during KD, and the relationship between the two is unclear. Herein, we report the case of a 17-month-old boy of KD with FS. Despite low predictive risk scores for initial intravenous immunoglobulin (IVIG) therapy failure, none of which include seizures as a risk factor, initial IVIG failed to provide symptom relief, necessitating a second IVIG and intravenous prednisolone. In KD, FS may themselves contribute to IVIG resistance.

Source: Ethiopian Journal of Pediatrics and Child Health

DOI: 10.4314/ejpch.v20i2.8

Authors: Tatsuya Iwasaki, Ryo Sugitate, Mariko Shimizu, Kensuke Tanaka, Atsushi Matsui

Institution: Maebashi Red Cross Hospital

Language: English

Topic: Kawasaki Disease and Coronary Complications

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4414131245

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