Get started
Work

Autophagy Upregulation in Mutant Isocitrate Dehydrogenase 1 (IDH1) Glioma Uncovers a Novel Therapeutic Target

Year: 2025
Type: preprint
DOI: 10.21203/rs.3.rs-7483444/v1
Authors: Maria Castro, Felipe Núñez, Kaushik Banerjee, Anzar Mujeeb, Ava Mauser, Claire Tronrud, Ziwen Zhu, Sadhakshi Raghuram, Maya Sheth, Jorge Armando Pena Agudelo, Julio Zelaya, Ayman Taher, Padma Kadiyala, Stephen Carney, Maria Garcia-Fabiani, Andrea Comba, Mahmoud Alghamri, Brandon McClellan, Zeribe Nwosu, Hanna Hong, Peter Sajjakulnukit, Tingting Qin, Maureen Sartor, Mats Ljungman, Joshua Welch, Shi-Yuan Cheng, Pedro Lowenstein, Joerg Lahann, Costas Lyssiotis
Institutions: University of Michigan, University of Alabama at Birmingham, Cornell University, Heidelberg University, University Medical Centre Mannheim, Medizinische Fakultät Mannheim, Michigan Medicine, Northwestern University
Language: English
Subfield: Genetics
Field: Medicine
Open Access status: green
Funders: National Science Foundation, Pediatric Brain Tumor Foundation, University of Minnesota, ChadTough Foundation, Ian's Friends Foundation, National Institutes of Health, University of California, San Francisco, National Cancer Institute, National Institute of Neurological Disorders and Stroke
Awards: G1662750671, G2101069996, G2357065241, G3241004844, G400135876, Chemo-immunotherapy strategy for pediatric high grade glioma, Stromal metabolism promotes therapeutic resistance in pancreatic cancer, G5330238478, G5561615526, Graduate Research Fellowship Program (GRFP), G9000085971, G9000180371, University of Michigan Rogel Cancer Center Support Grant 2023-2028, Systemic Delivery of Targeted Bi-Compartmental Nanoparticles for Glioblastoma Therapeutics, Uncover the role of H3.3-G343R mutation in shaping the DNA damage response, anti-tumor immunity and mechanisms of resistance in glioma., Role of the collagen receptor LAIR-1 in glioma progression and the tumor immune microenvironment, Neuro-immune mechanisms in mutant IDH1 gliomas, The Role of Collagen and its Signaling Mechanisms in Glioma Progression and Invasion.
OpenAlex ID: W4414136235
Cites:
Cited by:
Related to: 10