Work

A Randomized Comparative Study on the Effect of Dexmedetomidine and Magnesium Sulfate on Hemodynamics and Recovery Responses During Tracheal Extubation

Year: 2025

Type: article

Abstract: Emerging from general anesthesia (GA) and tracheal extubation can lead to unfavorable effects on hemodynamics, with complications from extubation occurring about three times more often than from intubation (12.6% vs 4.6%). 1 Tracheal extubation may temporarily increase heart rate (HR) and blood pressure (BP) by 10-30% for about 5-15 minutes due to automatic reflex sympathetic response from epipharyngeal to laryngopharyngeal stimulation.2,3 Coughing, straining, and breath holding have also been observed.While these changes are typically minor in healthy individuals, they may be of relevance with comorbidities such as hypertension, 4 coronary artery disease, 5 or cerebrovascular issues.6 Additionally, aggressive extubation

Source: Journal of Research & Innovation in Anesthesia

DOI: 10.5005/jp-journals-10049-2060

Authors: T Mohan Sankarji Maharaj, Manjula Venkatesh Ramsali, Mohan Rao Ambati, Sarada Devi Vankayalapati

Institution: Medicover Hospitals

Language: English

Topic: Anesthesia and Sedative Agents

Subfield: Anesthesiology and Pain Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4414139705

FWCI:

Cites: 24

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Related to: 10