Engineered mesenchymal stem cells-laden chondroitin sulfate hydrogel promotes diabetic wound healing through ROS scavenging and macrophage polarization
Year: 2025
Type: article
Abstract: investigations in diabetic mouse models further confirmed the therapeutic potential, revealing a significant acceleration of wound closure, attenuation of inflammation, and augmentation of angiogenesis. Overall, this innovative hydrogel system that encapsulates surface-engineered mesenchymal stem cells (MSCs-DCMMs) represents a promising remedy and a framework for stem-cell-based therapeutic systems to treat diabetic wounds.
Source: Materials Today Bio
Authors: Xi Cao, Ziqi Shen, Xiaohua Wang, Yuanyuan Chu, Runkong Wang, Liyang Zhu, Ruixue Zhong, Zhong Zhang, Mingquan Wu, Xu Zhou, Lei Zhang
Language: English
Topic: Wound Healing and Treatments
Subfield: Rehabilitation
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,400
Funders: National Natural Science Foundation of China, Anhui Medical University, State Administration of Traditional Chinese Medicine of the People's Republic of China, Anhui Provincial Department of Education, Scientific Research Foundation of Education Department of Anhui Province of China, Sichuan Province Science and Technology Support Program, Anhui Provincial Key Research and Development Plan
OpenAlex ID: W4414146863