Work

Synergistic effects of hyperbaric oxygen therapy combined with MPNFS nursing model on neurological recovery and recurrence prevention after chronic subdural hematoma surgery

Year: 2025

Type: article

Study designs: Randomized Controlled Trial, Clinical Trial

Abstract: Background: Chronic subdural hematoma (CSDH) has high postoperative recurrence rates. This study investigates the effects of hyperbaric oxygen therapy (HBOT) combined with Medical-Psychosocial-Nursing Functional Support (MPNFS) on functional recovery and recurrence prevention in CSDH patients, and establishes a recurrence prediction model. Methods: A total of 184 CSDH patients undergoing burr hole drainage were randomized into a control group and an observation group (HBOT + MPNFS). Neurological (NIHSS), motor (Fugl-Meyer Assessment), and quality-of-life (SF-36) outcomes were assessed preoperatively and at 1-month postoperatively. Complications and 6-month recurrence rates were recorded. Univariate/multivariate logistic regression identified recurrence risk factors, with ROC analysis evaluating predictive accuracy. Results: < 0.05). Independent recurrence predictors included brain atrophy (OR = 2.877), poor brain reexpansion (OR = 3.165), preoperative hematoma width ≥ 20 mm (OR = 2.782), and absence of combined intervention (OR = 2.842). The multifactorial model achieved an AUC of 0.7862, indicating robust predictive efficacy. Conclusion: Hyperbaric oxygen therapy combined with MPNFS enhances neurological/motor recovery, improves quality of life, and reduces complications/recurrence in postoperative CSDH patients.

Source: Frontiers in Neurology

DOI: 10.3389/fneur.2025.1642148

Authors: Ying Xie, Dongmei Yang, Ting Jiang, Hongdi Liu, Yan Gao

Institutions: Central South University, The First People's Hospital of Changde

Language: English

Topic: Neurosurgical Procedures and Complications

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801