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Thyroid dysfunction in non-alcoholic fatty liver disease: A case-control study

Year: 2025

Type: article

Abstract: Non-alcoholic fatty liver disease (NAFLD) is increasingly recognized as a hepatic manifestation of metabolic dysfunction, with emerging evidence linking it to thyroid abnormalities. In this case-control study of 120 adults, thyroid dysfunction was more prevalent in NAFLD cases, with 20% having overt hypothyroidism and 5% subclinical hypothyroidism. Thyroid dysfunction increased with NAFLD severity, with overt hypothyroidism observed in 66.7% of Grade 3 cases. These findings highlight a strong association between worsening thyroid function and NAFLD severity, suggesting the need for routine thyroid screening in NAFLD management.

Source: Bioinformation

DOI: 10.6026/973206300212453

Authors: Harshit Malkan, Bhavita Patel, Mahesh G Solu, Tejas D. Patel, Mahammed Kaif Mubrakhusen Bhaniya

Language: English

Topic: Liver Disease Diagnosis and Treatment

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4414147682

FWCI:

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