Resolution of Vulvar Lichen Sclerosus Symptoms Following Dietary Elimination of Tomato and Nightshade Vegetables: A Case Report
Year: 2025
Type: article
Study design: Case Report
Abstract: Lichen sclerosus (LS) is a chronic inflammatory skin condition that most often affects the perineal region and can greatly impact quality of life. This report presents the case of a 69-year-old woman with a 20-year history of vulvar LS. Despite standard treatment with topical corticosteroids, as well as multiple other therapies, including some nonstandard approaches, her symptoms persisted. Laboratory evaluation revealed elevated IgG antibodies to tomato. After eliminating tomatoes and other nightshade vegetables from her diet, the patient remained symptom-free for over a year. This case highlights a potential role of dietary antigens in LS and underscores the need for further investigation of non-IgE-mediated food sensitivities in managing symptoms.
Source: Cureus
DOI: 10.7759/cureus.91862
Author: Jill Hutton
Language: English
Topic: Genital Health and Disease
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4414148314