Work

Unilateral Gynecomastia and Primary Hypogonadism Following Brucellosis Infection: A Rare Case Report

Year: 2025

Type: article

Abstract: Brucellosis is a bacterial infection with a wide spectrum of clinical manifestations, yet endocrine complications such as primary hypogonadism and gynecomastia are exceedingly rare. We present the case of a 60-year-old male who was treated for brucellosis and, several weeks after discharge, developed unilateral enlargement of the left breast. Laboratory evaluation revealed significantly elevated gonadotropins (FSH and LH) with markedly decreased serum testosterone levels, indicating primary testicular failure. Sonographic imaging confirmed gynecomastia with a flame-shaped, irregular mass. This case highlights a rare hormonal sequela of brucellosis and emphasizes the importance of endocrine evaluation in patients who present with atypical manifestations following systemic infections.

Source: Clinical Case Reports

DOI: 10.1002/ccr3.70880

Author: Yaghoub Safdari

Institution: Golestan University of Medical Sciences

Language: English

Topic: Brucella: diagnosis, epidemiology, treatment

Subfield: Small Animals

Field: Veterinary

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,820