Work

High-Resolution Mapping of Tumor and Peritumoral Glutamate and Glutamine in Gliomas Using 7-T MRSI

Year: 2025

Type: article

Study design: Observational Study

Abstract: The 7-T MR spectroscopic imaging revealed increased glutamate and glutamine metabolic ratios within the peritumoral region compared with normal-appearing white matter in patients with glioma distinct from intratumoral changes, suggesting its potential clinical application for imaging glioma infiltration.

Source: Radiology Imaging Cancer

DOI: 10.1148/rycan.240494

Authors: Gilbert Hangel, Philipp Lazen, Cornelius Cadrien, Stefanie Chambers, Julia Furtner, Lukas Hingerl, Bernhard Strasser, Barbara Kiesel, Mario Mischkulnig, Matthias Preusser, Thomas Roetzer-Pejrimovsky, Adelheid Wöhrer, Wolfgang Bogner, Karl Rössler, Siegfried Trattnig, Georg Widhalm

Institutions: Medical University of Vienna, Danube Private University, Universität für Weiterbildung Krems, Innsbruck Medical University, Universität Innsbruck

Language: English

Topic: Advanced MRI Techniques and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: Austrian Federal Ministry of Economy, Family and Youth, Austrian Science Fund, Christian Doppler Forschungsgesellschaft

Award: 3D 2HG mapping as biomarker for IDH-mutation in glioma

OpenAlex ID: W4414160691

FWCI: 2.724

Cites: 40

Cited by: 5

Related to: 10