Work

Direct Vocal Fold Testosterone Injection for Treatment of Sulcus Vocalis: A Case Report

Year: 2025

Type: article

Abstract: This case report describes the use of targeted vocal fold testosterone injection as a novel, minimally invasive treatment for sulcus vocalis in a 28-year-old cisgender male with long-standing voice difficulties unresponsive to conventional therapies. He underwent two intramuscular testosterone injections into the thyroarytenoid muscle. Post-treatment, he demonstrated significant vocal improvements, including enhanced glottal competence, increased phonation time, and improved patient-reported outcomes, suggesting that androgen receptor stimulation may promote vocal fold remodeling as a potential alternative to surgical intervention.

Source: The Laryngoscope

DOI: 10.1002/lary.70129

Authors: Rohith S. Voora, Michelle K. Tenggara, Benjamin Schiedermayer, Andrew M. Vahabzadeh‐Hagh

Institution: University of California San Diego

Language: English

Topic: Voice and Speech Disorders

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,840