Work

Serotonin 5-HT2C Receptor Signaling Analysis Reveals Psychedelic Biased Agonism

Year: 2025

Type: article

Source: ACS Chemical Neuroscience

DOI: 10.1021/acschemneuro.5c00647

Authors: Emma M. Bonniwell, Rana Alabdali, Joseph J. Hennessey, John L. McKee, Natalie G. Cavalco, Josie C. Lammers, Ethan J. Moore, Luca Franchini, Cesare Orlandi, John D. McCorvy

Institutions: Medical College of Wisconsin, University of Rochester Medicine, University of Rochester

Language: English

Topic: Receptor Mechanisms and Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Institutes of Health, National Institute on Drug Abuse, National Institute on Deafness and Other Communication Disorders, National Institute of General Medical Sciences

Awards: Investigations into 5-HT2A signaling mechanisms of psychedelic drugs for the treatment of stimulant use disorder, G4829334056, G671887091, G9000332103, Discovery of synthetic and endogenous ligands for orphan GPCR GPR156

OpenAlex ID: W4414162276

FWCI: 1.515

Cites: 102

Cited by: 6

Related to: 10