Work

Authors' reply to letter regarding “Inflammaging links life's essential 8 to white matter brain aging”

Year: 2025

Type: letter

Abstract: We want to thank Dr. Grimolizzi's letter following up our study on Life's Essential 8 (LE8) and white matter brain aging.1 It is indeed of clinical interest to learn the underlying biological mechanism on how higher LE8 score helps maintain the integrity of white matter. We have previously found allostatic load (AL), a multi-system measure of the cumulative “wear and tear” on the body which includes inflammation,2 accelerated white matter brain aging.3

Source: EBioMedicine

DOI: 10.1016/j.ebiom.2025.105909

Authors: Tianzhou Ma, Zhenyao Ye, Li Feng, Shuo Chen

Language: English

Topic: Cardiovascular Health and Risk Factors

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $5,780

Funders: University of Maryland, National Institutes of Health, National Institute on Drug Abuse