Letter To the Editor in Response to: Hemolysis Induced by Pulsed-Field Ablation of Atrial Arrhythmias: A Comparative Analysis of Current Systems
Year: 2025
Type: preprint
Abstract: We read with great interest the recent article by Bruss J et al. on hemolysis induced by pulsed-field ablation (PFA) systems. The authors present compelling evidence that hemolysis varies substantially between catheter designs, with focal catheters such as the lattice-tip focal catheter (LTFC) resulting in significantly less hemolysis than large-footprint catheters like the pentaspline (PSC) and variable-loop circular catheter (VLCC). This analysis provides important insights into an under-recognized safety consideration, particularly as PFA continues to gain clinical momentum. We would like to highlight an additional and potentially modifiable contributor to hemolysis: intravenous fluid (IVF) administration.
Authors: Jonathan Schilling, Ali Sovari
Institution: Los Robles Hospital & Medical Center
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4414206993
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