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Novel Synergistic Synthesis of Ni-Doped Fe3O4 Nanocomposite: Adsorption Interactions with Heavy Metal Ions and Antimicrobial Studies of Hantzsch Products

Year: 2025

Type: article

Abstract: High Resolution Image Download MS PowerPoint Slide This study explores the synthesis, catalytic performance, and dual functionality of Ni@Fe 3 O 4 nanoparticles as both reusable catalysts and adsorbents for heavy metal ions. The Ni@Fe 3 O 4 nanoparticles efficiently catalyzed the one-pot synthesis of 1,4-dihydropyridine (1,4-DHP) derivatives, achieving high yields (89%–96%) with excellent purity, as confirmed by advanced spectroscopic techniques. The synthesized 1,4-DHP derivatives, particularly those with polar groups at the para position (compounds 3d, 3e, and 3f ), exhibited significant antimicrobial activity comparable to that of standard pharmaceutical drugs. Additionally, the Ni@Fe 3 O 4 nanoparticles exhibited high efficiency in adsorbing Pd(II) and Cu(II) ions, with optimal performance at a dosage of 0.07 g and pH 4, driven by enhanced protonation at acidic pH. The adsorption isotherm studies indicated a higher affinity for Pd(II), reaching a maximum adsorption capacity of 968.18 mg/g, while Cu(II) achieved 758.99 mg/g. These results underscore the versatility of Ni@Fe 3 O 4 nanoparticles as promising multifunctional materials for applications in organic synthesis, antimicrobial treatments, and environmental remediation of heavy metals.

Source: ACS Omega

DOI: 10.1021/acsomega.5c05934