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A Feasibility Study of Task-Based fMRI at 0.55 T

Year: 2025

Type: conference-paper

Abstract: Motivation: 0.55T MRI offers advantages compared to conventional field strengths, including reduced susceptibility artifacts and better compatibility with simultaneous EEG recordings. However, reliable task-based fMRI at 0.55T has not been significantly demonstrated. Goal(s): To establish a robust task-based fMRI protocol and analysis pipeline at 0.55T that achieves full brain coverage and results comparable to what is expected for activation extent and location. Approach: We attempted fMRI at 0.55T by combining EPI acquisition with custom analysis techniques. Finger-tapping and visual tasks compared 5 and 10-minute runs to enhance activation detection. Results: Significant activations demonstrating that high-quality task-based fMRI is achievable at 0.55T in single subjects. Impact: This study demonstrates that reliable task-based fMRI is feasible on 0.55T scanners, potentially broadening functional neuroimaging access in clinical and research settings where high-field MRI is unavailable or impractical, supporting broader diagnostic and research applications.

Source: Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition

DOI: 10.58530/2025/0491

Authors: Parsa Razmara, Takfarinas Medani, Anand A. Joshi, Majid Abbasi Sisara, Ye Tian, Sophia X. Cui, Justin P. Haldar, Krishna S. Nayak, Richard M. Leahy

Language: English

Topic: Advanced MRI Techniques and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4414235935

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