Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: Excessive daytime sleepiness (EDS), which is common in Parkinson's disease (PD), has been reported to exacerbate gait disturbance in patients with PD, but there is a lack of objective assessment, as well as an unknown specific mechanism. The purpose of our study is to explore the relationship between EDS and gait parameters. Methods: = 32) based on the scores of the Epworth Sleepiness Scale (ESS). The gait metrics of the two groups were then assessed by wearable devices and compared under various walking scenarios. Results: Compared with the non-EDS group, the EDS group showed significantly shorter step lengths and stride lengths, slower walk speed and gait speed, reduced shank-max forward swing and sagittal angular velocity, and increased phase coordination indices and mean duration of turns. Pearson correlation analysis revealed a significant association between ESS scores and various gait parameters. Furthermore, multiple linear regression analysis confirmed that EDS is an independent factor influencing gait in patients with PD. Conclusion: EDS was independently associated with gait disturbances in patients with PD, suggesting that EDS symptoms warrant serious attention in clinical practice.
Source: Frontiers in Aging Neuroscience
Authors: Yibo Xie, Maoyun Zhao, Yanjie Guo, Panpan Tian, Sheng Liu, Hongxia Xing
Language: English
Field: Health Professions
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,801
Award: G6009025920
OpenAlex ID: W4414253665