Year: 2025
Type: article
Abstract: Recent advancements in pharmaceutical manufacturing are paving the way for highly personalized and on-demand therapies. This article discusses a novel approach that integrates Hot Melt Extrusion (HME) with 3D printing to produce drug dosage forms with customizable immediate- and modified-release profiles. By transforming APIs and polymers into drug-loaded filaments and then precisely printing them into dosage forms, this method addresses longstanding challenges, such as limited control over drug distribution and suboptimal solubility, while enhancing patient compliance. The innovative design not only promises tailored dosing regimens but also provides significant advantages in production efficiency and regulatory compliance. Keywords: Personalized Medicine, Hot Melt Extrusion (HME), Solubility, Patient Compliance
Authors: Amit Kumar, Pooja Arora
Language: English
Subfield: Automotive Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4414257610