Atypical Presentation of Meningococcemia as Gastroenteritis in an Adult: A Case Report
Year: 2025
Type: article
Study design: Case Report
Abstract: Meningococcal disease is a life-threatening infection that can present with diverse and sometimes atypical manifestations, making early diagnosis challenging. We report the case of a 29-year-old man who presented with acute gastrointestinal symptoms, raising suspicion for gastroenteritis. Blood cultures later identified Neisseria meningitidis serogroup W135, confirming a diagnosis of meningococcemia. Unlike the typical presentation of meningococcal disease in adults, which often features fever, hypotension, myalgias, and a characteristic petechial rash, this patient exhibited predominantly gastrointestinal manifestations without neurologic signs or rash, leading to an early diagnostic challenge. Prompt recognition and empirical antibiotic treatment resulted in rapid clinical improvement and prevention of complications. This case underscores the importance of maintaining a high index of suspicion for meningococcemia in adults presenting with sepsis, even in the absence of classic features, as early intervention remains critical to improving outcomes.
Source: Cureus
DOI: 10.7759/cureus.92126
Institutions: Hamad Medical Corporation, Ministry of Public Health
Language: English
Subfield: Microbiology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4414261472