Work

Synthesis, Structure–Activity Relationships, and Antitumor Activities of Quinoxiline-Containing Inhibitors of the Protein–Protein Interactions between Transcription Coactivator AF9/ENL and DOT1L/AF4

Year: 2025

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.5c01587

Authors: Chandra Bhushan Mishra, Xin Li, Bala Krishna Moku, Sehun Kwak, Dnyaneshwar N. Garad, Yongcheng Song

Institutions: Baylor College of Medicine, Dan L Duncan Comprehensive Cancer Center

Language: English

Topic: Synthesis and Biological Evaluation

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: closed

Funder: National Cancer Institute

Award: Novel Small-Molecule Probes Targeting Oncogenic Fusion MLL in Pediatric Leukemia

OpenAlex ID: W4414264377

FWCI: 1.159

Cites: 31

Cited by: 4

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