Relationship between maternal obesity, birth weight, and fetal adiponectin/leptin ratio: a potential early biomarker of cardiometabolic risk
Year: 2025
Type: article
Study design: Observational Study
Abstract: This study is the first to explore the association between fetal adiponectin/leptin (AdipoQ/Lep) ratio and maternal and neonatal anthropometrics and early alterations in cardiac structure. Although maternal and neonatal weight metrics impact infant heart development, this occurs independently of the AdipoQ/Lep. However, lower levels of AdipoQ/Lep ratio were associated with reduced Z-score of left ventricular end-diastolic diameter, offering insights into fetal programming mechanisms linked to maternal metabolic status during pregnancy.
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Awards: Early Cardiovascular, Metabolic and Histological Changes Identified in Children Born from Pregnant Women with Risk Factors., Unidade de Investigação e Desenvolvimento Cardiovascular, G6586625987, HEALTH-UNORTE: Setting-up biobanks and regenerative medicine strategies to boost research in cardiovascular, musculoskeletal, neurological, oncological, immunological and infectious diseases, The impact of maternal diet and weight on postpartum cardiac remodelling / reverse remodelling – the role of gut microbiota, Unidade de Investigação e Desenvolvimento Cardiovascular
OpenAlex ID: W4414276589