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Cas9 Protein Outperforms mRNA in Lipid Nanoparticle-Mediated CFTR Repair

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Year: 2025
Type: article
Source: Nano Letters
DOI: 10.1021/acs.nanolett.5c03548
Authors: Ryann A. Joseph, Rebecca M. Haley, Marshall S. Padilla, Adele S. Ricciardi, Hannah M. Yamagata, Michael J. Mitchell
Institutions: University of Pennsylvania, Children's Hospital of Philadelphia, Abramson Cancer Center
Language: English

Topic: RNA Interference and Gene Delivery
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Center for Undergraduate Research and Fellowships, University of Pennsylvania, American Cancer Society, Burroughs Wellcome Fund, Cystic Fibrosis Foundation, University of Pennsylvania, National Institutes of Health, National Institute of Dental and Craniofacial Research, Division of Chemical, Bioengineering, Environmental, and Transport Systems, National Science Foundation Graduate Research Fellowship Program
Awards: A data-driven drug delivery (4D) platform for probing and treating the chemoresistant bone marrow microenvironment, G185654730, G2867495689, Bone marrow vascular microenvironment combination RNAi-bortezomib nanotherapy for multiple myeloma, Advanced Training at the Interface of Engineering and Oral-Craniofacial Sciences
OpenAlex ID: W4414281168
FWCI: 0.761
Cites: 27
Cited by: 3
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