Serum amyloid A concentration in naturally infected cats with Hepatozoon felis alone or coinfected with other pathogens
Year: 2025
Type: article
Abstract: Feline hepatozoonosis, caused by Hepatozoon felis and occasionally other Hepatozoon species, is a vector-borne disease transmitted through the ingestion of infected arthropods, primarily ticks. This study investigates serum amyloid A, a major acute-phase protein, in cats naturally infected with H. felis or co-infected with other vector-borne pathogens. A total of 41 asymptomatic, infected cats were categorized into single or co-infection groups, alongside 12 healthy controls. Serum amyloid A levels were measured using enzyme-linked immunosorbent assay and analyzed statistically. Results showed no significant association between serum amyloid A concentrations and variables such as co-infection status or pathogen load. Although levels of this acute phase protein were slightly lower in co-infected cats, findings suggest that serum amyloid A alone may have limited diagnostic utility in distinguishing these co-infections.
Institution: Universidad de Zaragoza
Language: English
Subfield: Parasitology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W4414295025
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