Unmasking the Emotional and Behavioral Determinants of Glycemic Control in Diabetes Management
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background In type 2 diabetes mellitus (T2DM), glycemic regulation is influenced not only by physiological parameters but also by behavioral patterns, emotional states, and socioeconomic variables. These nonclinical factors are increasingly recognized for their potential role in personalizing diabetes care. Objectives This study examined the influence of behavioral factors (such as medication adherence and diabetes self-care), diabetes-related emotional distress, and socioeconomic status, in addition to clinical determinants, on glycemic control among urban Indian individuals with T2DM. Methods This cross-sectional investigation enrolled adult patients with T2DM. Socioeconomic classification was performed using the Modified Kuppuswamy Scale (2022). Medication adherence was assessed with the Morisky Medication Adherence Scale 4-item, while behavioral and emotional components were evaluated using the Diabetes Self-Management Questionnaire and the Diabetes Distress Scale. Comprehensive patient profiles, including anthropometry, lipid panels, and body-fat metrics, were collected. Associations between the variables of interest and glycemic status were examined using chi-square analysis. Results Higher self-management scores were significantly associated with favorable glycemic profiles (χ² = 9.574, p = 0.008). Elevated diabetes-related emotional distress showed a strong association with glycemic outcomes (χ² = 9.6824, p = 0.007), even among patients who maintained their glycemic targets. Notably, all subjects reported some degree of distress. Socioeconomic factors, central obesity, and triglyceride and high-density lipoprotein levels influenced adherence patterns and access to care. Conclusions Effective glycemic control in T2DM is closely linked to behavioral adherence and emotional resilience. These findings underscore the importance of integrative, patient-tailored approaches that account for psychological and contextual factors, particularly in culturally diverse and resource-variable settings.
Source: Cureus
DOI: 10.7759/cureus.92635
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4414312268