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Allele-specific conformational rescue of KIF1A T99M by genetic suppressors in a C. elegans model of KIF1A-associated neurological disorder

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Year: 2025
Type: article
Source: Journal of Cell Science
DOI: 10.1242/jcs.264216
Authors: Zihan Chen, Yongping Chai, Zhengyang Guo, Xuanyu Fu, Wei Li, Jinxiang Zhang, Guangshuo Ou, Hui Wang
Institutions: Huazhong University of Science and Technology, Center for Life Sciences, State Key Laboratory of Membrane Biology, Tsinghua University, Wuhan Union Hospital
Language: English

Topic: Microtubule and mitosis dynamics
Subfield: Cell Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Tsinghua University, Key Technologies Research and Development Program, National Key Research and Development Program of China
Awards: G1581902037, G1588936196, G1717995342, G1801876202, G2316205668, G3616413942, G4384616021, G4569828870, G5327568564, G6125328427, G6701647352, G7242039958, G8191189953, G8989934138
OpenAlex ID: W4414335449
FWCI: 0.421
Cites: 58
Cited by: 1
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