Laparoscopic resection of retroperitoneal metastasis originating from sternal leiomyosarcoma – a case report
Year: 2025
Type: article
Study design: Case Report
Abstract: Background: Leiomyosarcomas are malignancies of smooth muscle differentiation that can metastasize early through hematogenous spread.Leiomyosarcoma of the sternum is extremely rare, with an incidence of < 0.7% among malignant bone tumors.Case: We report the case of a 66-year-old male with a retroperitoneal metastasis located in the right pararenal space, originating from a sternal leiomyosarcoma.Three years earlier, the patient had undergone partial excision of the sternum and costal cartilages, fol lowed by thoracic wall osteosynthesis, for the primary tumor.Fol low-up imaging with CT and PET-CT revealed a mass in the right perirenal space, situated between the upper pole of the right kidney and the right adrenal gland.In the absence of other metastatic lesions and fol lowing multidisciplinary oncology team discussion, the patient underwent laparoscopic en bloc metastasectomy and right adrenalectomy.Results: Histopathological examination confirmed the metastatic nature of the tumor with negative resection margins.Postoperatively, the patient experienced fever due to atelectasis, which resolved with intravenous antibio tics.He was discharged on the 6 th postoperative day and remains free of recurrence at a two-year fol low-up.Conclusion: Minimally invasive surgical techniques allow for oncological resection of retroperitoneal metastatic lesions with low perioperative morbidity and mortality.Resection of isolated lymph node metastases has been shown to improve overall survival and dis ease control. Key words retroperitoneal metastasis -lymph node metastasis -leiomyosarcoma -sternum -minimally invasive metastasectomy -adrenalectomyThe authors declare that they have no potential conflicts of interest concerning drugs, products, or services used in the study.Autoři deklarují, že v souvislosti s předmětem studie nemají žádné komerční zájmy.
Source: Klinicka onkologie
DOI: 10.48095/ccko2025302
Authors: Orestis Ioannidis, Efstathios Cotidis, Elissavet Anestiadou, Ioannis Matzarakis, James Philip Skliris, Savvas Symeonidis, Stefanos Bitsianis, Ourania Kerasidou, Magda Kaprianou, Christiana Chatzianestiadou, Eleni Salta-Poupnara, Freiderikos Tserkezidis, Konstantinos Angelopolos, Stamatios Angelopoulos
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4414341373
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