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[Expression of Concern] Downregulation of miR‑145 contributes to lung adenocarcinoma cell growth to form brain metastases

Year: 2025

Type: article

Abstract: Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that, regarding the cell migration and invasion assay experiments shown in Fig. 4, the 'Mock' data panel in Fig. 4A‑a (A549 cell line, migration assay) was apparently identical to the 'Mock' data panel in Fig. 4B‑b (SPC‑A1 cell line, invasion assay), even though the reported experimental conditions were different. The authors were contacted by the Editorial Office to offer an explanation for this apparent data duplication; however, up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further. [Oncology Reports 30: 2027‑2034, 2013; DOI: 10.3892/or.2013.2728].

Source: Oncology Reports

DOI: 10.3892/or.2025.8991

Authors: Chunyang Zhao, Yan Xu, Yongqiang Zhang, Weiwei Tan, Jianxin Xue, Zongze Yang, You Zhang, You Lu, Xun Hu

Institutions: Sichuan University, West China Hospital of Sichuan University, State Key Laboratory of Biotherapy

Language: English

Topic: MicroRNA in disease regulation

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4414344772

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