Autoimmune Haemolytic Anaemia: A report of two cases with varied clinical course managed at the Kenyatta National Hospital, Nairobi, Kenya
Year: 2025
Type: article
Study design: Case Report
Abstract: Autoimmune Haemolytic Anaemia (AIHA) is a rare yet serious condition characterized by immune-mediated red cell destruction. It presents with anaemia, jaundice, and splenomegaly, requiring a high index of suspicion for timely diagnosis. We present two cases managed at the Kenyatta National Hospital (KNH), highlighting varied disease courses and treatment responses. Management includes corticosteroids as first-line therapy, with immunosuppressants or biologics like rituximab for refractory cases. Limited access to diagnostic tests and treatment options remains a challenge in Kenya. Addressing these barriers through improved clinician awareness and healthcare infrastructure is crucial for optimizing AIHA outcomes in resource-limited settings.
DOI: 10.4314/jkap.v7i2.5
Authors: Debbie Mwende Mutua, Matilda Ong’ondi
Institution: University of Nairobi
Language: English
Topic: Blood groups and transfusion
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4414353070
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