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How I do it: > 8 Carmustine wafer implantation during supra-marginal resection of a glioblastoma, IDH-wildtype

Year: 2025

Type: article

Abstract: BACKGROUND: The maximal safe resection of glioblastoma, IDH-wildtype often creates a large resection cavity that can accommodate more than eight Carmustine implants. METHOD: We detail the implantation technique of 13 Carmustine wafers within the surgical bed after a right hippocampal formation-sparing anterior temporal lobectomy allowing for the supra-marginal resection of a glioblastoma IDH-wildtype in an adult patient. CONCLUSION: Carmustine wafer implantation is a safe and efficient technique following surgical resection of a glioblastoma, IDH-wildtype. Sequential technical steps are required to improve the safety and the efficacy of Carmustine wafer implantation. More than eight Carmustine wafers could be implanted in large surgical cavities with survival benefits for the patients.

Source: Acta Neurochirurgica

DOI: 10.1007/s00701-025-06675-5

Authors: Alexandre Roux, Angela Elia, Marc Zanello, Johan Pallud

Institutions: Inserm, Université Paris Cité, Centre Hospitalier Sainte-Anne, Institut de Psychiatrie et Neurosciences de Paris, GHU Paris psychiatrie & neurosciences

Language: English

Topic: Glioma Diagnosis and Treatment

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,990