Work

Positron Emission Tomography/Computed Tomography in Ovarian Cancer: Current Status and Future Potential

Year: 2025

Type: article

Abstract: ABSTRACT Ovarian cancer (OC) is the most lethal gynecological malignancy. Diagnosis usually occurs late, and even with the most effective treatment relapses are frequent. Early diagnosis and precise staging are critical for achieving better treatment outcomes and prognoses. Conventional imaging methods such as ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI) are the main imaging techniques supporting management decisions. However, advancements in molecular imaging have made positron emission tomography/computed tomography (PET/CT) a promising noninvasive imaging option for better management of OC. The literature provides evidence indicating that fluorine‐18‐fluorodeoxyglucose ( 18 F‐FDG) PET/CT (FDG‐PET/CT) is effective in primary tumor diagnosis, staging, prognosis evaluation, treatment response assessment, and relapse surveillance. Looking ahead, significant attention should be paid to tracers beyond FDG, integrated PET/MRI, dynamic PET, and artificial intelligence (AI)‐based radiomics. This review examines the application of PET/CT in OC management at each disease stage and discusses its future potential.

Source: iRadiology

DOI: 10.1002/ird3.70034

Authors: Caiyun Xu, Jing Peng, Jinyan Chen, Lixia Zhang, Jing Wang

Institutions: Zhejiang Chinese Medical University, Zhejiang Cancer Hospital, Zhejiang University

Language: English

Topic: Medical Imaging Techniques and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: National Natural Science Foundation of China, Department of Education of Zhejiang Province, Medical and Health Research Project of Zhejiang Province, Key Research and Development Program of Zhejiang Province