Effects of aerobic exercise on cognitive function in patients with type 2 diabetes mellitus: a meta-analysis
Year: 2025
Type: review
Study designs: Systematic Review, Meta-Analysis
Abstract: Type 2 diabetes mellitus(T2DM) is a chronic metabolic disease that adversely affects cognitive function. Aerobic exercise, an important non-pharmacological intervention, has controversial effects on cognitive function. The goal of this study was to systematically assess the effects of aerobic exercise on cognitive function in patients with T2DM . Seven electronic literature databases were searched: PubMed, Web of Science, Embase, Cochrane Library, Wanfang Data, CNKI, and VIP. The search was conducted from the time of construction to June 2025. The data were analyzed using RevMan5.4.1 and stata17. A total of nine studies with 841 patients were included in this study, 410 in the experimental group and 431 in the control group. The results showed that aerobic exercise had a significant effect on cognitive function in patients with T2DM [SMD=0.94, 95% CI (0.63, 1.25), P<0.00001]. Aerobic exercise significantly improves cognitive function in patients with T2DM, but more large-sample, high-quality randomized controlled trials are needed in the future.
DOI: 10.54691/7r1a1m23
Authors: Yuanyuan Wang, Mengtin Pan, Baojian Wei, Huiwen Sun, Jing Huang
Institution: Southwest University
Language: English
Topic: Physical Activity and Health
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4414367045