A Clinical Evaluation of Immediate Implant Placement with/without PRF in Anterior Esthetic Zone
Year: 2025
Type: article
Study design: Clinical Trial
Abstract: Aim: The present study aimed to determine the implant mobility, bleeding on probing, and marginal bone level after immediate implant placement with or without platelet-rich fibrin (PRF) in the anterior esthetic zone. Materials and methods:The present study included forty patients aged between 18 and 45 years.Patients were allocated into two groups: Group I: Control group (n = 20): Patients who had immediate implant placement without PRF, group II: Test group (n = 20): Patients who had immediate implant placement with PRF.Immediately before the procedure, PRF preparation for the test group proceeded.Implant insertion was performed right after following tooth extraction.To evaluate the effectiveness of immediate implant placement with or without PRF, the clinical parameters such as implant mobility, bleeding on probing, and marginal bone level were measured at baseline, 3 months, and 6 months.Data was recorded and statistically analyzed.Results: Implant mobility in the third month was three (15%) and one (5%), and in the sixth month was four (20%) and two (10%) in control and test group, respectively.In the control group, at baseline, bleeding on probing was 1.10 ± 0.06; it increased at the sixth month to 1.42 ± 0.02.In the test group, at baseline, bleeding on probing was 1.08 ± 0.01; it increased at the sixth month to 1.26 ± 0.04.In the control group, in the third month mean marginal bone level was 0.58 ± 0.08 and 0.60 ± 0.10, and in the sixth month, 0.64 ± 0.01 and 0.72 ± 0.06 in the control and test group, respectively.There was a significant difference found at the third and sixth months between the groups.Conclusion: The present study concluded that immediate implant placement with the PRF group showed better improvement in implant mobility, bleeding on probing, and marginal bone level.Clinical significance: Platelet-rich fibrin progressively releases substantial amounts of thrombospondin-1 and growth factors.PRF is considered a healing biomaterial that uses circulating stem cells to stimulate key elements of soft and osseous tissue repair, such as angiogenesis and immunological regulation.In order to promote the healing process at the surgical site, PRF is crucial in the esthetic zone.
Authors: Naman Awasthi, Subhash Sonkesriya, Sitesh K Samal, Upasana Reddy, Maya HM Felmban, Shetty Hardik Santosh
Institutions: KIIT University, Nitte University, Batterjee Medical College
Language: English
Subfield: Oral Surgery
Field: Dentistry
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4414376370