Year: 2025
Type: article
Abstract: Nanotechnology is revolutionizing pharmaceutical industry and drug development by providing significant advantages in controlling drug release, enhancing stability, and reducing adverse effects. Concurrently, natural products are being extensively researched for their anticancer and immunomodulatory properties. This patent review aims to analyze publications that integrate nanotechnology with natural products to develop cancer treatments and immunotherapies. In this context, 17 patents were identified through the free online databases of the European Patent Office (EPO) and the World Intellectual Property Organization (WIPO). The review discusses various types of nanotechnology, including nanoparticles, nanocarriers, and nanocapsules, as well as bioactive compounds primarily extracted from plants. Among the most frequently identified natural products were ursolic acid, hyaluronic acid, and catechins. These bioactive compounds have been shown to promote cell cycle arrest, reduce tumor size, and exhibit synergistic effects with other anticancer agents. Consequently, the combination of natural products with nanotechnology holds significant therapeutic potential.
Authors: Jan Filipe Andrade Santos, Marcela Bernardes Brasileiro, Pamela Danielle Cavalcante Barreto, Ligiane Aranha Rocha, José Adão Carvalho Nascimento Júnior
Institution: Universidade Federal de Sergipe
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4414390979