Association of Hyperuricemia With the Presence and Severity of Coronary Artery Disease in Patients Undergoing Coronary Angiography
Year: 2025
Type: article
Study design: Observational Study
Abstract: Introduction: Coronary artery disease (CAD) is on the list of leading causes of morbidity and mortality in the world. Hyperuricemia is no longer a benign disease or metabolic disorder since studies have found an increasing correlation of hyperuricemia and cardiovascular risk and the severity of CAD. Objective: To identify the relationship that exists between hyperuricemia and the severity and occurrence of CAD among patients who were undergoing coronary angiography in a tertiary care hospital. Materials and Methods: A cross-sectional study was conducted from July, 2024 to December, 2024 at the Rashid Latif Medical College, Lahore. A sample size of 250 patients who received coronary angiography was involved. The level of serum uric acid and the severity of CAD based on Gensini score were determined. Data analysis was performed using SPSS 26. Results: The prevalence of hyperuricemia was 41.6 percent. An increased uric acid was linked to increased prevalence of the triple vessel disease and a much higher percentage of mean Gensini scores in the normouricemic patients. Conclusion: Hyperuricemia was significantly associated with each and severity of CAD which justifies its position as a mere adjunctive risk stratification marker.
DOI: 10.53555/7fxe4g94
Author: Muhammad Ahmad Raza Butt
Language: English
Subfield: Nephrology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4414394325
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