Year: 2025
Type: article
Study design: Observational Study
Abstract: Objective: The aim of this study is to evaluate the prognostic value of the C-reactive protein (CRP)/albumin ratio (CAR) compared to the Simplified Pulmonary Embolism Severity Index (sPESI)in predicting 30-day and 180-day mortality in patients with pulmonary embolism (PE). Materials and Methods:This retrospective cross-sectional study included patients over 18 years of age, diagnosed with PE and admitted to the intensive care or pulmonary diseases departments.The study investigated the relationship between CRP/CAR, sPESI, and clinical outcomes such as 30-day and 180-day mortality, and hospital admissions.Results: Among 111 patients, 17 died within 180 days and 7 within 30 days.While no significant association was found between 30-day mortality and the CRP/CAR or the sPESI the CRP/CAR was significantly higher in those with 180-day mortality (p<0.001).The area under the curve (AUC) for the CRP/CAR in predicting 180-day mortality was 0.782 (p<0.001),compared to 0.593 for the the sPESI(p=0.224).The DeLong test confirmed the superior predictive performance of the CRP/CAR. Conclusion:This study shows that the CRP/CAR has greater prognostic value than the sPESI in predicting 180-day mortality in PE patients, though no significant association was found for 30-day mortality.
Authors: Serkan Günay, Salih Yağcı, Ahmet Öztürk, Gürbüz Meral, İrem Hacer Türkmen, Yasemin Arı Yılmaz, Seval Komut, Yavuz Yiğit, Ali Kemal Erenler
Language: English
Subfield: Internal Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4414394463
FWCI:
Cites:
Cited by:
Related to: