Work

Use of a digital rescue inhaler and at-home spirometer among inner-city children with asthma: a real-world experience

Year: 2025

Type: article

Abstract: Background: Across all age groups, asthma disproportionally affects inner-city underserved populations. Studies on the use of at-home spirometry and digital inhalers have limited real-world evaluation in pediatric asthma. Objectives: In this prospective exploratory study, we assessed how an integrated digital rescue inhaler and at-home spirometer would affect proper inhaler use, medication adherence, and asthma outcomes using a minimalistic real-world approach. Methods: In total, 21 pediatric patients with asthma (8-17 years of age) were asked to replace rescue medications with the ProAir Digihaler and perform at-home gamified spirometry daily. Lung function and questionnaires were obtained at baseline and at 3-4 months. Results: The participants were mostly male (81%), Latino/Hispanic (71%), and obese (88th ±16 percentile). Proper rescue inhaler step identification by survey did not change, but inhalation technique based on digital inhaler flow measurements improved for all participants. At-home spirometry was sporadic and reported controller adherence did not change. Younger children (age 8-11) were more severe at baseline [Composite Asthma Severity Index (CASI) of 4.8] compared to older children (CASI of 2.9). For younger children, overall asthma control test scores increased by 3.1, CASI decreased by 0.70, and the Pediatric Quality of Life Inventory scores increased by 14 and 11 for participants and parents, respectively. Conclusions: Proper rescue inhaler step identification by survey did not change, but actual inhalation technique based on digital inhaler flow measurements improved. At-home spirometry was sporadic and reported medication adherence did not change. Younger children used the spirometer more frequently and demonstrated improvements in asthma control, severity, and quality of life. These improvements were not observed in older children.

Source: Frontiers in Allergy

DOI: 10.3389/falgy.2025.1641312

Authors: Neema Izadi, Tanisha D. Hill, Amanda Boe, Daisy Yu, Jonathan S. Tam

Institutions: Children's Hospital of Los Angeles, Teva Pharmaceuticals (United States)

Language: English

Topic: Asthma and respiratory diseases

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,077