Work

Synthesis and characterization of new phthalocyanines providing effective singlet oxygen production and comparison of photochemically and sonophotochemically methods

Year: 2025

Type: article

Abstract: The recently significant results in effective medical treatment in Sonophotodynamic Therapy (SPDT) applications have highlighted the importance of the design of new sonosensitizers/sonophotosensitizers. Thanks to their versalite molecular structure and tunable photophsicochemical features, phthalocyanines have gained remarkalbe attention. Encouraged by these results bis 4-[(6-bromonaphthalene-2)-ol] substituted metallophthalocyanines at peripheral positions were synthesized and characterized. The singlet oxygen production capacities of the newly synthesized compounds were investigated in sonochemically, photochemically and sonophotochemically. In all experiments, InPc-4 have highest singlet oxygen production capacity. Zn-Pc and Mg-Pc singlet oxygen quantum yield were 0.38 and 0.28 in photochemical methods. Obtained result showed that, InPc is a promising sensitizer for all application. On the other hand MgPc and ZnPc are suitable for sonophotochemically applications.

Source: Polyhedron

DOI: 10.1016/j.poly.2025.117792

Authors: Fulya Aksoy, Fatma Aytan Kılıçarslan, Ceren Can Karanlık, Ali Erdoğmuş

Institution: Yıldız Technical University

Language: English

Topic: Porphyrin and Phthalocyanine Chemistry

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $3,740

Funder: Yildiz Teknik Üniversitesi