Minimum effective low dose of antithymocyte globulin in people aged 5–25 years with recent-onset stage 3 type 1 diabetes (MELD-ATG): a phase 2, multicentre, double-blind, randomised, placebo-controlled, adaptive dose-ranging trial
Year: 2025
Type: article
Study designs: Randomized Controlled Trial, Clinical Trial
Source: The Lancet
Authors: Chantal Mathieu, Julie Wych, A Emile J Hendriks, Lisa Van Ryckeghem, Timothy Tree, Piotr Chmura, Christopher Möller, Kristina Casteels, Thomas Danne, Felix Reschke, Darja Šmigoc Schweiger, Tadej Battelino, Jesper Johannesen, Birgit Rami-Merhar, Thomas Pieber, Christophe De Block, Mark Evans, Robert Hilbrands, Emanuele Bosi, Ruben H Willemsen, Supriyo Basu, Mari-Anne Pulkkinen, Mikael Knip, Miriam Cnop, Almut Nitsche, Anke M Schulte, Elisabeth Niemöller, Mark Peakman, Charlotte Wilhelm-Benartzi, David Gillespie, Lut Overbergh, Adrian P Mander, M Loredana Marcovecchio, Chantal Mathieu, Lutgart Overbergh, Mark Evans, A. Emile J. Hendriks, M. Loredana Marcovecchio, Mark Peakman, Timothy Tree, Noel G. Morgan, John A. Todd, Linda Wicker, Adrian P. Mander, Colin M Dayan, Julie Wych, David Gillespie, Thomas Pieber, Decio L. Eizirik, Miriam Cnop, Søren Brunak, Flemming Pociot, Jesper Johannesen, Roberto Mallone, Mikael Knip, Timo Otonkoski, Riitta Veijola, Riitta Lahesmaa, Anette G. Ziegler, Michele Solimena, Ezio Bonifacio, Reinhard Holl, Francesco Dotta, Francesco Chiarelli, Piero Marchetti, Emanuele Bosi, Stefano Cianfarani, Carine de Beaufort, Knut Dahl-Jørgensen, Przemyslawa Jarosz-Chobot, Tadej Battelino, Martin Gotthardt, Bart O. Roep, Markus Lundgren, Guillaume Costecalde, Matthias von Herrath, Antonella Napolitano-Rosen, Elisabeth Niemöller, Stefanie Keil, Sanjoy Dutta, Esther Latres, Gina Agiostratidou, Anne Koralova
Institutions: Universitair Ziekenhuis Leuven, KU Leuven, Cardiff University, University of Cambridge, Cambridge University Hospitals NHS Foundation Trust, King's College London, University of Copenhagen, Novo Nordisk Foundation, Kinderkrankenhaus auf der Bult, University of Ljubljana, Ljubljana University Medical Centre, Steno Diabetes Centers, Herlev Hospital, Copenhagen University Hospital, Steno Diabetes Center Copenhagen, Medical University of Vienna, Medical University of Graz, University of Antwerp, Antwerp University Hospital, Vrije Universiteit Brussel, Vita-Salute San Raffaele University, IRCCS Ospedale San Raffaele, Barts Health NHS Trust, Oxford University Hospitals NHS Trust, University of Helsinki, Helsinki University Hospital, Université Libre de Bruxelles, Erasmus Hospital, Sanofi (Germany)
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: green
Funders: Eli Lilly and Company, Sanofi, Leona M. and Harry B. Helmsley Charitable Trust, European Federation of Pharmaceutical Industries and Associations, Insulet Corporation, Innovative Health Initiative, University of Cambridge, University of Oxford, European Commission, Novo Nordisk, Innovative Medicines Initiative, Horizon 2020 Framework Programme, Abbott Diabetes Care, Universitaire Ziekenhuizen Leuven, KU Leuven, JDRF
OpenAlex ID: W4414400011