Work

Incidental Ovarian Vein Thrombosis During Breast Cancer Therapy With Tamoxifen and Trastuzumab

Year: 2025

Type: article

Abstract: Ovarian vein thrombosis (OVT) is an unusual presentation of venous thromboembolic disease. Incidental asymptomatic appearance of OVT is a recognized complication of gynecologic cancer surgery, but published information on incidental OVT during targeted therapy of cancer with hormone therapy and/or monoclonal antibodies is scarce. We present the case of a 41-year-old woman who had a diagnosis of asymptomatic right OVT during the adjuvant treatment of breast cancer with tamoxifen plus trastuzumab. Clinical evolution in this case was favorable without anticoagulant therapy, with confirmed thrombus resolution and without further events. Available literature on this topic is limited, but some data indicate that anticoagulation is also a valuable option to consider, according to potential advantages and risks, on an individual basis.

Source: Cureus

DOI: 10.7759/cureus.92955

Authors: Jorge Illarramendi, Susana Mauleon, Helena Sarasibar, Jose Juan Illarramendi

Institutions: Hôpital Cardiologique du Haut-Lévêque, Clinica Universidad de Navarra

Language: English

Topic: Venous Thromboembolism Diagnosis and Management

Subfield: Internal Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4414400506