Acute Scrotal Ulcers in a 34-Year-Old Male With an Excellent Treatment Response: A Case Report
Year: 2025
Type: article
Study design: Case Report
Abstract: Juvenile gangrenous vasculitis of the scrotum (JGVS) is a rare disease, but it has a distinct presentation and a favourable response to treatment. In this clinical case, we present a male patient in his early 30s with tender scrotal ulcers, no history of sexually transmitted diseases or risk behaviours, and no previous systemic disease or immunosuppression. Studies revealed elevated inflammatory markers, but remarkably, all microbiologic studies were negative. The patient was diagnosed with JGVS and was treated with methylprednisolone 24 mg, tapered over two months, in combination with doxycycline 100 mg BID for one month, and topical clobetasol under occlusion, with complete healing in two months and no relapse. This case contributes to the existing knowledge of JGVS. Typically, patients are young, usually under 30 years old; however, this patient was slightly older. While exclusive scrotal involvement is common, this patient also exhibited smaller satellite ulcers on the adjacent thigh.
Source: Cureus
DOI: 10.7759/cureus.92952
Authors: João N Soares, Maria M Brites, Jose C Cardoso
Institutions: Unidade Local de Saúde de Coimbra, University of Coimbra
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4414401556