Work

Cationic iridium( iii ) complexes with a halogen-substituted pyridylbenzimidazole ancillary ligand for photodynamic therapy

Year: 2025

Type: article

Abstract: Halogenated Ir( iii ) complexes show tuneable photophysical properties, dual ROS generation, and strong mitochondrial phototoxicity; Ir-F and Ir-H stand out as promising theranostic agents for image-guided photodynamic cancer therapy.

Source: Materials Advances

DOI: 10.1039/d5ma00964b

Authors: Pierre-Henri Lanoë, Frédérique Loiseau, Christian Philouze, Camille Latouche, Laetitia Vanwonterghem, Louis Biancon, Ahmed S. Faihan, Florian Molton, Matéo Lavaud, Anne-Laure Bulin, Jean-Luc Coll, Akos Banyasz, Amandine Hurbin

Institutions: Centre National de la Recherche Scientifique, Département de Chimie Moléculaire, Université Grenoble Alpes, Institut Universitaire de France, Institut des Matériaux Jean Rouxel, Nantes Université, Inserm, Institut pour l'avancée des biosciences, Lyon 1 Université, École Normale Supérieure de Lyon, Laboratoire de Chimie

Language: English

Topic: Photodynamic Therapy Research Studies

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

Open Access status: gold

Estimated APC paid: $1,962

Funders: European Commission, Agence Nationale de la Recherche, HORIZON EUROPE European Research Council

Awards: G1183670895, CBH-EUR-GS, G2121614283, G2659019386, Nanoscintillators to potentiate brain cancer radiotherapy: from physics to preclinical trials, G292453335, IDEX UGA, G6803667113, G994248709

OpenAlex ID: W4414418199

FWCI: 1.765

Cites: 74

Cited by: 3

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