Endoscopic ultrasound safety and efficacy in pediatric pancreatobiliary and gastrointestinal disorders: single-center retrospective trial
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background While endoscopic ultrasound (EUS) is well established as a standard diagnostic and therapeutic tool in adults, its use in children remains limited. This study assessed the indications, safety, and clinical impact of diagnostic and therapeutic EUS in children with pancreatobiliary and gastrointestinal disorders. Methods We retrospectively analyzed pediatric patients with pancreatobiliary and gastrointestinal disorders wh9o underwent EUS at our institution between January 2022 and June 2025. Results Fifty-three EUS procedures were conducted in children with a median age of 9.6 ± 3.0 years. Indications for EUS included acute recurrent pancreatitis (n = 15), suspected chronic pancreatitis (n = 12), suspected choledocholithiasis (n = 7), obstructive jaundice (n = 5), pancreatic mass (n = 1), gastric mucosal lesions (n = 6), suspected esophageal lymphoma recurrence (n = 1), suspected autoimmune hepatitis (n = 1) and pancreatic pseudocyst (PPC, n = 5). ERCP was performed during the same anesthesia for all children requiring it post-EUS. Five patients underwent cystogastrostomy for symptomatic PPC with 100% technical and clinical success. The efficacy of EUS in guiding definitive therapeutic decisions and invasive interventions was 100%. Notably, no major complications occurred. Conclusion EUS is safe and effective diagnostic and therapeutic modality in pediatric patients with pancreatobiliary and gastrointestinal disorders.
Source: Frontiers in Pediatrics
Authors: Jiayu Zhang, Zhaohui Deng
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,801
OpenAlex ID: W4414426973