Terpenes as Naturally Occurring Stereochemical Templates: Conformationally Driven Discovery of Reactivity
Year: 2025
Type: article
Abstract: High Resolution Image Download MS PowerPoint Slide Natural terpene-derived substrates have been used as stereochemical templates in the gold(I)-catalyzed cycloisomerization of aliphatic 1-bromoalkynes. The conformational restrictions imposed by these substrates have unlocked an unprecedented 5- exo cyclization mode in gold catalysis. This reactivity was extended to structurally simplified substrates.
Source: Organic Letters
Authors: Omar Arto, Rubén Miguélez, Hannah Siera, Jan Schulte, Isabel Merino, Gebhard Haberhauer, Pablo Barrio
Institutions: Universidad de Oviedo, University of Duisburg-Essen
Language: English
Topic: Catalytic Alkyne Reactions
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: hybrid
Estimated APC paid: $4,500
OpenAlex ID: W4414428778