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Clinical Reasoning: A 40-Year-Old Man With Refractory Status Epilepticus After Small Bowel Resection for Volvulus

Year: 2025

Type: article

Abstract: Evaluating and treating patients with altered mental status in the intensive care unit can be complicated. In this case, a 40-year-old man presented with small bowel volvulus and his course was complicated by super-refractory status epilepticus (SRSE). Repeated attempts to wean ketamine infusion led to recurrence of SE. This case details the approach for evaluation and management of SRSE. Owing to the patient's intolerance to ketamine infusion weaning, we opted for the off-label use of the oral NMDA receptor antagonist memantine, which successfully supported the weaning process from ketamine infusion.

Source: Neurology

DOI: 10.1212/wnl.0000000000214182

Authors: Akash Chakravartty, Emily J. Gilmore, Lawrence J. Hirsch, Michele Moura, Rachel B. Beekman

Institutions: Yale University, Yale New Haven Health System

Language: English

Topic: Epilepsy research and treatment

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4414434399

FWCI:

Cites: 15

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