Year: 2025
Type: article
Study design: Systematic Review
Abstract: Objective: The primary aim of this study is to provide a comprehensive analysis of the pharmacological interventions targeting the mechanisms of aging. 1) To categorize and describe the different classes of anti-aging drugs, including antioxidants, senolytics, telomerase activators, and hormone replacement therapies. 2) To analyze recent research findings on anti-aging therapeutics. 3) To analyze growth trajectory of anti-aging drugs globally. Methods: This analysis was conducted by systematically searching scientific databases, including PubMed, Scopus, and Web of Science, for articles published between 2000 and 2025 related to anti-aging drugs and their mechanisms of action. Results: The research analysis identified ten major classes of anti-aging drugs, with senolytics and caloric restriction mimetics showing the most promise. Emerging therapies like NAD⁺ precursors, stem cell treatments, and antibody-based approaches are under active investigation. The global anti-aging drug market is growing rapidly, driven by innovation and increased demand for longevity solutions. Conclusion: The exploration of anti-aging drugs through a pharmacological lens highlights the significant advancements and challenges in this field.
Authors: SATYENDRA NARAYAN TIWARI, TUSHAR C. BAHETI, RAJESH C. S., RAJ K. SHARMA
Institution: Chirayu Medical College & Hospital
Language: English
Subfield: Aging
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4414437994