Work

Left atrioventricular valve durability in atrioventricular septal defects: Impact of systolic blood pressure

Year: 2025

Type: article

Abstract: Objective: To evaluate the impact of systolic blood pressure (SBP) on the durability of left atrioventricular valve (LAVV) repair in the early postoperative period. Methods: Single-center, retrospective review of 88 consecutive patients undergoing atrioventricular septal defect (AVSD) repair over 5 years. Postoperative transesophageal echocardiogram and discharge transthoracic echocardiogram were compared, and patients who experienced deterioration in valve function were identified. Results: = .023). Incremental increases in peak SBP were linearly associated with valve deterioration starting at a peak SBP >150 mm Hg. SBP >160 mm Hg was identified as an independent predictor of valve deterioration on multivariate logistic regression, while patient weight, gestational age, primary diagnosis, cardiopulmonary bypass time, cross-clamp time, and cleft closure were not predictive of valve deterioration. Conclusions: Elevated SBP during the early postoperative period is associated with functional LAVV deterioration. Elevated peak SBP >160 mm Hg was associated with worse LAVV function. Strict control of blood pressure to avoid even transient elevations in SBP during the postoperative period may improve LAVV durability.

Source: JTCVS Open

DOI: 10.1016/j.xjon.2025.09.022

Authors: Christina L. Greene, Teklay Desta, Anjali Sharma, David Mauchley, Lyubomyr Bohuta, D. Michael McMullan

Institutions: Seattle Children's Hospital, University of Washington

Language: English

Topic: Congenital Heart Disease Studies

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,431